IDENTIFYING INVERSIONS WITH BREAKPOINTS IN THE DYSTROPHIN GENE THROUGH LONG-READ SEQUENCING: REPORT OF TWO CASES

Identifying inversions with breakpoints in the Dystrophin gene through long-read sequencing: report of two cases

Abstract Background Duchenne Muscular Dystrophy (DMD) is an X-linked disorder caused by mutations in the DMD gene, with large deletions being the most common type of mutation.Inversions involving the DMD rosaliac ar intense visible facial redness serum gene are a less frequent cause of the disorder, largely because they often evade detection by sta

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Bet-hedging strategies in expanding populations.

In ecology, species can mitigate their extinction risks in uncertain environments by diversifying individual phenotypes.This observation is quantified by the theory of bet-hedging, which provides a reason for the degree of phenotypic diversity observed even in clonal populations.Bet-hedging in well-mixed populations is rather well understood.Howeve

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Comprehensive analysis of vaginal microbiota in Chinese women with genital tuberculosis: implications for diagnosis and treatment

Abstract Background Tuberculosis remains an infectious disease of global concern, with potential impacts on respiratory and intestinal microbiota owing to prolonged broad-spectrum antibiotic therapy.Despite its potential to cause infertility, the vaginal microbiota of women with genital tuberculosis remains poorly understood.We comprehensively anal

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Cost-effectiveness of trastuzumab deruxtecan as a second-line treatment for HER2-mutant advanced non-small cell lung cancer

The study of DESTINY-Lung01 and DESTINY-Lung02 demonstrated the favorable efficacy and optimal dosage of trastuzumab deruxtecan (T-DXd) in managing the human epidermal growth factor receptor 2 (HER2)-mutant non-small cell lung cancer (NSCLC) patients who had received previous treatment.The study sought to assess the cost-effectiveness of T-DXd in m

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Study the basic building wooden structures to withstand the effects of weather and destructive biological agents Alborz research center

With full respect for the principles of linking wood and conservation project Eldar pine because having good mechanical properties and availability of a wood structure in the form of pavilions chose alcove to the octagon without internal column with computer software Sketch up of Alborz research center with trees and landscaping of angilina white t

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